Welcome to Santi’s Restaurante Mexicano, a vibrant gem nestled at 1302 Meeting St, Charleston, SC 29405. This delightful Mexican restaurant invites you to indulge in the rich tapestry of flavors and traditions that Mexican cuisine has to offer. As you step inside, you're greeted by a lively atmosphere filled with colorful decor and the warm sounds of Hispanic music, setting the stage for an unforgettable dining experience.
Santi’s is known for its delectable offerings, combining authentic recipes with fresh ingredients. From the moment you glance at the menu, your senses will be tantalized by choices such as the Milanesa Breaded Steak and the Tampiqueña, featuring perfectly grilled skirt steak accompanied by comforting sides. Each dish is thoughtfully prepared, as seen in the reviews from satisfied patrons like Tuung Thunm and Lisa Warhol, who praise not only the quality and flavors but also the attentive service that makes every guest feel welcome.
Don’t miss the opportunity to delight in their desserts, especially the Bomba Chocolate-covered Gelato and the classic Churros—treats that promise to cap off your meal with just the right amount of sweetness. Reviewers have raved about the handmade tortillas, contributing to the authentic taste that makes every bite a joy.
The heartwarming experiences shared by guests underscore Santi's commitment to flavorful food and a friendly atmosphere. Whether you’re diving into their Enchiladas Verdes for lunch or enjoying a cozy dinner with family, you’ll find that Santi’s is not just a restaurant; it's a community hub that embraces the spirit of Mexican culture.
With quick service and a menu that pleases everyone—from the casual diner to the discerning foodie—Santi’s Restaurante Mexicano is ready to welcome you. Give them a call at +1 843-722-2633 to reserve a spot, and prepare yourself for an authentic culinary adventure that celebrates the rich flavors of Mexico.
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Lisa Warhol
21/10/2025
I came with my family of 6. They helped with all my dietary requests as well as for my nephew who is very picky. The service is super nice and understanding. Place is super cute. Food came out incredibly fast. Food was very tasty and good portions. Music is hispanic and good. Definitely a good time!!
Joe LaMartina
05/09/2025
We had wanted some Latin food and remembered we had been by Santi's on several occasions so we stopped in Very nicely decorated with a ton of pictures decoration and music Service was quick, I think we had our food in less that 15 minutes and it was delicious. We will be back again loved the food and atmosphere.
Caroline C. Duncan, MD, FMCHC
02/09/2025
Lovely experience! We each had an entree and a shot of Luna Azul tequila with a beer. Nice and spicy salsa. So many comforting trinkets and decor. Fast.
Tuung Thunm
11/08/2025
I had a great experience at Santi’s Restaurante Mexicano on Meeting Street. I ordered 3 tacos, and they were fantastic—fresh, flavorful, and made with quality ingredients. The service was friendly and attentive without being rushed, and the food came out quickly. The atmosphere has a welcoming, laid-back vibe that makes it easy to relax and enjoy your meal. It feels like a local gem in Charleston, and I can definitely see myself coming back again soon. Highly recommend for anyone craving authentic Mexican food!
Jessica Black
09/08/2025
We went here for supper in late October and the decorations were so beautiful! We ate inside and our waitress was so nice!! The food was soo good! I had the beef tacos and the tortillas where definitely hand made! So fluffy and flavorful! Highly recommend
Jennifer Donkle
07/07/2025
Love! Love! LOVE!! So glad my daughter suggested Santi’s…it is funky, the food is delicious, and the servers are friendly and attentive. The salsa has just a hint of heat and the chips were tasty. And my veggie burrito was yummy!! I will definitely be eating here again!
Nina Cash
06/07/2025
It was the perfect day to sit outside and Santi’s has this amazing jungle feel to their outdoor patio with the sun peeking through the trees and the nice breeze was so nice. They had a pretty extensive menu and a lot of options so I was feeling torn. They offered authentic Mexican tacos which I love (American style was an option too) Our servers were two very nice ladies and were very attentive despite how busy they were. I was happy to find out they had Caipirinha’s! My friend nachos were a huge, I got the enchiladas verde which was good and the star dish was the camarones a la diablo. If you love shrimp, garlic and spice. You HAVE to get this dish. It was seriously addicting and you got this delicious homemade guacamole that they put back inside a half shell which I thought was so cool. I am literally only eating that from now on when I come here. It was a great time with friends and food!